Zebrafish Market Size, Share, Growth, and Industry Analysis, By Product Type (Toxicity Testing Services, Transgenesis and Gene Editing Services, Disease Models and Others), By Application (Pharmaceutical, Biotechnology, Agrochemical Research, Cosmetics, Water Quality Monitoring and Others), Regional Outlook, and Forecast From 2025 To 2033

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ZEBRAFISH MARKET REPORT OVERVIEW

The global zebrafish market size was valued at approximately USD 0.13 billion in 2024 and is expected to reach USD 0.46 billion by 2033, growing at a compound annual growth rate (CAGR) of about 14.5% from 2025 to 2033.

Freshwater fish in the minnow family (Cyprinidae) of the order Cypriniformes include the zebrafish (Danio rerio). It is a well-known aquarium fish that is native to South Asia and is commonly offered under the trade name zebra danio. Despite being both tropical and subtropical, it is frequently referred to as a "tropical fish." Additionally, private ponds contain it. In scientific study, this fish is a significant and frequently used vertebrate model organism, for instance in drug development, particularly pre-clinical development. It is remarkable for its capacity for regeneration, and scientists have altered it to create a variety of transgenic variants.

COVID-19 Impact: The Intrinsic COVID-19 Condition Curtailed the Market Growth

The global COVID-19 pandemic has been unprecedented and staggering, with the zebrafish market experiencing lower-than-anticipated demand across all regions compared to pre-pandemic levels. The sudden spike in CAGR is attributable to demand returning to pre-pandemic levels once the pandemic is over.

The COVID-19 epidemic severely damaged the world's healthcare system. Hospitals and clinics had to deal with a number of issues, including a lack of resources, a massive influx of patients, and the risk of infection among medical staff. Due to the pandemic and the suspension and postponement of elective surgeries, including dental procedures, the zebrafish market share suffered.

LATEST TRENDS

"Introduction as a Modal System to Study Obesity to Surge the Market Demand "

The fish have been utilized as model organisms for the study of obesity in both hereditary and over nutrition-induced forms. Obese zebrafish exhibit dysregulation of lipid-controlling metabolic pathways, which causes weight growth without proper lipid metabolism, just like obese vertebrates do. Like mammals, the fish also store extra lipids in subcutaneous, intramuscular, and visceral adipose tissue. The fish are suitable models to investigate obesity in humans and other species for the aforementioned factors as well as others. In transgenic or mutant zebrafish with obesogenic genes, genetic obesity is typically examined.

The fish’s models of diet-induced obesity are helpful because diets can be changed starting at a very young age. Both high-fat diets and diets that generally overfeed the body result in rapid increases in adiposity, BMI, hepatosteatosis, and hypertriglyceridemia. However, the regular fat, overfed specimens still have a healthy metabolism, unlike the specimens on a high-fat diet. Understanding the variations in feeding-induced obesity could be helpful in treating obesity in people as well as other related health issues.

ZEBRAFISH MARKET SEGMENTATION

• By Product Type

Based on materials the zebrafish market is classified into toxicity testing services, transgenesis and gene editing services, disease models and others.

Toxicity testing services is the leading part of the material segment.

• By Application

Based on application the zebrafish market is classified as pharmaceutical, biotechnology, agrochemical research, cosmetics, water quality monitoring and others.

Pharmaceuticals are the leading part of the application segment.

DRIVING FACTORS

"The Several Transgenic Modal to Study Cancer to Boost the Market Share "

Several transgenic cancer models, including melanoma, leukaemia, pancreatic cancer, and hepatocellular carcinoma, have been created using zebrafish. It has raised on a background lacking p53 develop melanoma when they exhibit mutant versions of the BRAF or NRAS oncogenes. These tumours reveal extensive genetic changes, closely match the human disease histologically, and are completely transplantable.

The model was employed in one study as a tool to comprehend the functional significance of genes that were amplified and over-expressed in human melanoma. One gene, SETDB1, significantly sped up tumour development in the the fish’s model, highlighting its significance as a novel melanoma oncogene. Because SETDB1 is known to be involved in the epigenetic control that is becoming more recognized as being essential to tumour cell biology, this was particularly noteworthy.

"The Utilization of Product as a Modal System to Study Diabetes to Attract the Consumers"

The zebrafish pancreas develops extremely similarly to mice and other mammals. The pancreas's functioning and the signalling systems are remarkably similar. There is an endocrine compartment in the pancreas that houses a number of cells. Two examples of these cells are the insulin-producing -cells and the polypeptide-producing pancreatic PP cells. This pancreatic anatomy and the glucose homeostasis system are important for understanding disorders like diabetes that have a pancreatic component.

The mechanisms of glucose homeostasis and pancreas development can be understood using models for pancreas function, such as fluorescent protein staining. The fish were utilized in the development of the glucose tolerance tests that are now used to diagnose diabetes and glucose intolerance in people. The fish are also being used to study insulin function, which will benefit human medicine. The majority of research on glucose homeostasis has been conducted in the fish and has been applied to humans.

RESTRAINING FACTORS

"Certain Limitations and Disadvantage with the Solubility to Repel the Market Players"

Despite the adaptability of zebrafish, there are some research fields where they are not the best model, such as human disorders in tissues or organs that don't have the fish’s analogue (prostrate, mammary glands, lungs). They are aquatic species, so some research may run into problems because of their habitat. The fact that some medications are not soluble in water, making submersion delivery difficult, is another drawback of the the fish model. Therefore, the certain limitation and disadvantage being a restraining factor can hamper the zebrafish market growth in the forecasted period.

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ZEBRAFISH MARKET REGIONAL INSIGHTS

"European Region to Dominate the Market with Rising Rodents Modal Organisms"

Europe is the largest market accounting for about 40% of share globally. In fundamental biological research, zebrafish are a more and more common model organism. The number of fish increased by 28.5% between 2008 and 2011, according to the most recent report from the European Commission on the quantity of animals used in research in the EU. The increasing employment of fish in scientific study is sometimes viewed as a major success in the replacement of mammalian model species, particularly rodents. To ensure that any research using the fish can be conducted in accordance with the same scientific and animal welfare criteria as the laboratory rodents they frequently replace, methodologies and methods are urgently needed given the increasing relevance of the fish as an animal model.

KEY INDUSTRY PLAYERS

"Prominent Manufacturers to Contribute Towards Expansion of Market"

The report is an extensive research which presents the historic and futuristic performance of industry with competitive landscape analysis which incorporates prominent key players, and revenue trends of industry.

List Of Top Zebrafish Companies

• Shanghai Model Organisms Center, Inc. (China)
• ZeClinics (Spain)
• InVivo Biosystems (U.S.)
• Biobide (U.K)
• Pentagrit (India)
• Evotec (Germany)
• Aurigene Pharmaceutical Services (India)
• Hangzhou Hunter Biotechnology Co., Ltd. (China)
• YSY BIOTECH (U.S.)
• INVENesis (Switzerland)
• FEIFAN TEST (Australia)
• Charles River Laboratories (U.S).

REPORT COVERAGE

The report anticipates a detailed analysis of the global market size at the regional and national level, the segmentation market growth and market share. The prime objective of the report is to help user understand the market in terms of definition, market potential, influencing trends, and the challenges faced by the market. Analysis of sales, the impact of the market players, recent developments, opportunity analysis, strategic market growth analysis, territorial market expansion, and technological innovations are the subject matter explained in the report.